Image is an illustration, may not reflect the exact product sold.


Other products by Sigma Aldrich / MilliporeSigma

Sigma Aldrich / MilliporeSigma - ZRB1308-25UL - Anti-Myosin Heavy Chain 7 Antibody, clone 1B19, ZooMAb Rabbit Monoclonal

  • MFR SKU: ZRB1308-25UL
  • ITEM #: 16666197
  • 12345
    • 0 out of 5 stars
    • 5 Star
      0 %
    • 4 Star
      0 %
    • 3 Star
      0 %
    • 2 Star
      0 %
    • 1 Star
      0 %
  • 0 Reviews / 0 Questions
$293.75
  • +
    -

  • Please complete this captcha to continue

Stock Status: SHIPS SOON (reserve your unit today)

  • Please complete this captcha to continue

    * Please log into your account to avoid entering this information every time.


ITEM #: 16666197
ZRB1308-25UL Anti-Myosin Heavy Chain 7 Antibody, clone 1B19
This listing is for Each.

Sigma Aldrich / MilliporeSigma - ZRB1308-25UL - Anti-Myosin Heavy Chain 7 Antibody, clone 1B19, ZooMAb<SUP></SUP> Rabbit Monoclonal

  • Item #: 16666197
  • MFR SKU: ZRB1308-25UL
Technical Specs
  • General description: We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Green antibody is Preservative-free, produced without the harm or sacrifice of animals and exceptionally stable to allow for ambient shipping and storage if needed and thus aligns with ".
  • Waste Prevention", ".
  • Designing Safer Chemicals" and ".
  • Design for Energy Efficiency". Click here for more information. ZooMAb antibodies represent an entirely new generation of recombinant monoclonal antibodies. Each ZooMAb antibody is manufactured using our proprietary recombinant expression system, purified to homogeneity, and precisely dispensed to produce robust and highly reproducible lot-to-lot consistency. Only top-performing clones are released for use by researchers. Each antibody is validated for high specificity and affinity across multiple applications, including its most commonly used application. ZooMAb antibodies are reliably available and ready to ship when you need them. Learn more about ZooMAb here. Specificity: Clone 1B19 is a ZooMAb rabbit recombinant monoclonal antibody that specifically detects Myosin -7. It targets an epitope within 13 amino acids from the N-terminal region. Immunogen: KLH-conjugated linear peptide corresponding to 13 amino acids from the N-terminal region of human Myosin heavy chain 7. Application: Anti-Myosin Heavy Chain 7, clone 1B19 ZooMAb, Cat. No. ZRB1308, is a recombinant rabbit monoclonal antibody that specifically detects Myosin Heavy Chain 7 and has been tested for use in Affinity Binding Assay ELISA, Immunohistochemistry (Paraffin), and Western Blotting. ELISA Analysis: 0.5 g/mL from a representative lot of Anti-Myosin Heavy Chain 7, clone 1B19 ZooMAb Rabbit Monoclonal detected Myosin Heavy Chain 7, but not any other peptide from 6 other (Paraffin) Analysis: A 1:100-1, 000 dilution from a representative lot detected Myosin Heavy Chain 7 in human skeletal muscle and mouse skeletal muscle tissue Binding Assay: A representative lot of this antibody bound Myosin Heavy Chain 7 with a KD value of 2.51 x 10-7 in an affinity binding assay. Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user. Target description: Myosin-7 (UniProt: P12883; also known as Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, Myosin heavy chain cardiac muscle beta isoform, MyHC-beta) is encoded by the MYH7 (also known as MYHCB) gene (Gene ID: 4625) in human. Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Myosins form regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Fast and slow mammalian muscle myosins differ in their heavy chain sequences. Muscles expressing the two isoforms contract at markedly different velocities. Myosin-7 is a component of thick filaments of the myofibrils. It contains actin- and ATP-binding sites in its conserved catalytic head domain. Mutations in MYH7 gene are known to cause familial hypertrophic cardiomyopathy that is characterized by ventricular hypertrophy leading to dyspnea, syncope, collapse, palpitations, and chest pain. This ZooMAb recombinant monoclonal antibody, generated by our propriety technology, offers significantly enhanced specificity, affinity, reproducibility, and stability over conventional monoclonals. (Ref.: Iorga, B., et al. (2007). J. Biol. Chem. 282(6); 3559-3670). Physical form: Purified recombinant rabbit monoclonal antibody IgG, lyophilized in PBS with 5% Trehalose, normal appearance a coarse or translucent resin. Contains no biocide or preservatives, such as azide, or any animal by-products. Larger pack sizes provided as multiples of 25 L. Reconstitution: 300 g/mL after reconstitution at 25 L per vial. Please refer to guidance on suggested starting dilutions and/or titers per application and sample type. Storage and Stability: Recommend storage of lyophilized product at 2-8C.
  • Before reconstitution, micro-centrifuge vials briefly to spin down material to bottom of the vial.
  • Reconstitute each vial by adding 25 L of filtered lab grade water or PBS.
  • Reconstituted antibodies can be stored at 2-8C, or -20C for long term storage. Avoid repeated freeze-thaws., biological source: rabbit (recombinant), Quality Level: 200, recombinant: expressed in HEK 293 cells, conjugate: unconjugated, antibody form: purified antibody, antibody product type: primary antibodies, clone: 1B19, monoclonal recombinant monoclonal, product line: ZooMAb learn more, form: lyophilized, mol wt: calculated mol wt 223.10kDa. biological source - rabbit (recombinant), Quality Level - 200, recombinant - expressed in HEK 293 cells, conjugate - unconjugated, antibody form - purified antibody, antibody product type - primary antibodies, clone - 1B19, monoclonal, recombinant monoclonal, product line - ZooMAb< SUP>®</SUP> < A HREF='/technical-documents/technical-article/protein-biology/immunohistochemistry/zoomab-recombinant-monoclonal-antibodies' target='_blank'>learn more</a>, form - lyophilized, mol wt - calculated mol wt 223.10 kDa, species reactivity - rat, mouse, human, packaging - antibody small pack of 25 μ L, greener alternative product characteristics - Waste Prevention< BR/>.
  • Designing Safer Chemicals< BR/>.
  • Design for Energy Efficiency< BR/>.
  • Learn more about the < A HREF='/life-science/ssbi/green-chemistry-principles'>.
  • Principles of Green Chemistry</a>., enhanced validation - recombinant expression< BR/>.
  • Learn more about < A HREF='/technical-documents/technical-article/protein-biology/immunohistochemistry/antibody-enhanced-validation'>.
  • Antibody Enhanced Validation</a>, sustainability - Greener Alternative Product, technique(s) - ELISA: suitable, affinity binding assay: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable, isotype - IgG, UniProt accession no. - <a href=' /uniprot/P12883'> P12883</a>, greener alternative category - < A HREF='/life-science/ssbi/greener-products-solutions'>.
  • Aligned</a>, < A HREF='/life-science/ssbi/greener-products-solutions'></a>, shipped in - ambient, storage temp. - 2-8° C, target post-translational modification - unmodified, Gene Information - human ... MYH7(4625)< BR>mouse ... Myh7(140781)< BR>rat ... Myh7(29557)
Questions & Answers

There are no questions about this product yet. Be the first to ask a question.

Add Question
0 Customer Ratings & Reviews
12345
0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Write a review

Recently Viewed Items