Toll Free 1.866.636.2487
NEOBITS
Cart
ITEMS IN CART: 0  TOTAL: $0.00


CALL TOLL FREE
1.866.636.2487


PerkinElmer - AL502F - IL-10 (mouse) AlphaLISA Detection Kit, 5, 000 Assay Points

PerkinElmer - AL502F - IL-10 (mouse) AlphaLISA Detection Kit, 5, 000 Assay Points
Image is an illustration, may not reflect the exact product sold.
10206597
AL502F

PerkinElmer - AL502F - IL-10 (mouse) AlphaLISA Detection Kit, 5, 000 Assay Points

Call For Stock
(Shipping delay possible)
$11,921.50
Request Quote

The AlphaLISA Mouse Interleukin-10 (IL-10) Detection Kit is designed for detection and quantitation of mouse IL-10 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. Formats: Our 500 assay point kit allows you to run 500 wells in 96-well or 384-well format, using a 50 µL reaction volume (5 µL of sample). Our 5, 000 assay point kit allows you to run 5, 000 wells in 96-well or 384-well format, using a 50 µL reaction volume (5 µL of sample). Features: No-wash steps, no separation steps ELISA alternative technology Sensitive detection Broad sample compatibility Small sample volume Results in less than 3 hours Half the time of an ELISA assay In the mouse, Interleukin 10 (IL10), first characterized as a Cytokine Synthesis Inhibitory Factor (CSIF), is a 160 amino acid protein noncovalently associated in a homodimer. In humans, IL10 is produced by various T cell populations, monocytes, macrophages, and other cell types. IL10 activity is mediated by the heteromeric IL10 receptor (IL10R). IL10 inhibits interferon-? synthesis in Th1 cells and monocytes, and inhibits IL12 production by monocytes. It also impairs the proliferation and cytokine synthesis of CD4+ T cells, without having a direct inhibitory affect on CD8+ T cells. On the other hand, IL10 has a stimulatory influence on B cells. In general, its main biological functions are to limit and terminate the inflammatory responses, block proinflammatory cytokine secretion, and regulate the differentiation and proliferation of several immune cells. AlphaLISA technology allows the detection of molecules of interest in a no-wash, highly sensitive, quantitative assay. In an AlphaLISA assay, a biotinylated anti-analyte antibody binds to the Streptavidin-coated Donor beads while another anti-analyte antibody is conjugated to AlphaLISA Acceptor beads. In the presence of the analyte, the beads come into close proximity. The excitation of the Donor beads causes the release of singlet oxygen molecules that triggers a cascade of energy transfer in the Acceptor beads, resulting in a sharp peak of light emission at 615 nm.

See other products in some related categories (click to browse):
Assay Target: IL10 Assay Target Class: Cytokine Automation Compatible: Yes Detection Method: Alpha Experimental Type: In vitro Product Brand Name: AlphaLISA Shipping Condition: Blue Ice Target Species: Mouse Therapeutic Area: Inflammation Unit Size: 5, 000 assay points


Neobits.com is where business goes shopping. With over 5 million products from 10,000+ manufacturers, we offer the largest B2B catalog on the internet (to our knowledge). We cater to the needs of all major verticals, small to large businesses, government, education and healthcare markets, as well as consumers. Through our extensive, carefully developed supplier and logistics network we have instant access to over $100 billion worth of inventory in hundreds of stocking warehouses nationwide. We ship to every state and to nearly 100 countries worldwide.

Our categories include Industrial & Scientific, MRO Products & Supplies, Laboratory & Science, Electronic Components, Occupational Health & Safety, Electronics, Computer & Photo, Access Control & Security, Wireless Carrier Infrastructure, Test & Maintenance, and thousands more. That said, the best way to find products on our website is via search. We are always expanding our catalog, with thousands of new products added daily. If you need something you don't see here, email us at , or call toll free 1.866.636.2487. Prospective new suppliers, please email .

We can send formal quotes or bids upon request. Please submit this form to request a quote. We often have volume discounts, government & education discounts and loyalty discounts. We accept purchase orders from government and public education entities, as well as publicly traded corporations. CAGE Code: 3P0S1.

We are continually investing in people and systems to offer excellent customer service. See some customer testimonials here. You can reach our Customer Care team via email at , or call toll free 1.866.636.2487. The best way to request a return or order cancellation is to submit this form.

Also see: Categories, Products, Brands and Top Searches.


Creditcards Logos
Credit Card Processing
Acceptance Mark View Neobits, Inc. profile on Ariba Discovery