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AdipoGen - 40B0005TDT100 - Annexin V (human) (rec.) (ATTO 488) (Each)

AdipoGen - 40B0005TDT100 - Annexin V (human) (rec.) (ATTO 488) (Each)
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6167206
40B0005TDT100

AdipoGen - 40B0005TDT100 - Annexin V (human) (rec.) (ATTO 488) (Each)

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$258.40

Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

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Host E. coli Conjugate ATTO 488 Form Liquid. Size 100 tests Unit Each Clonality Protein Long Term Storage +4°C Molecular Weight ~52kDa (SDS-PAGE) Purity >95% (SDS-PAGE) Sequence Recombinant human annexin V fused to a GST-tag. Short Term Storage +4°C Species Crossreactivity Human Specificity Binds to phosphatidylserine (PS). Stability Stable for at least 1 year after receipt when stored at +4°C. Storage Buffer In PBS, pH 7.4, containing 0.02% sodium azide.


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